This chapter investigates the intricate relationship between environmental change and wildlife health, with a focus on novel perspectives. Stress, a key player in wildlife health, can impact immunity, reproduction, and survival. Research in this domain is in its infancy but holds potential for innovative conservation strategies. Additionally, we examine unconventional stressors like light and noise pollution, presenting emerging threats and potential mitigation strategies. We advocate for interdisciplinary collaboration involving ecologists, environmental scientists, psychologists, and the use of cutting-edge technologies like remote sensing and artificial intelligence. These tools empower us to monitor wildlife health and analyze data effectively. Our findings underline the urgency of reducing greenhouse gas emissions, protecting habitats, reducing pollution, and minimizing human impact on wildlife. We invite individuals to join these efforts. In summary, this chapter highlights the interconnectedness of wildlife health and the well-being of our planet, emphasizing our moral duty to protect these sentient beings for a healthier world.