Surgical facelifting, while providing significant results for facial rejuvenation, is often associated with substantial complications and extended recovery periods. This has driven the increasing popularity of less invasive alternatives over the last decade, such as thread lifting. Thread-lifting procedure offers a compelling solution with faster recovery, reduced risk, and immediate patient satisfaction. It involves inserting absorbable sutures, such as the commonly used Definisse threads, beneath the skin to elevate and reposition sagging tissue. Definisse threads are fourth-generation threads made from a copolymer of L-lactide and ε-caprolactone and feature a tridimensional barbed design. This unique structure provides a dual mechanism of action: a sustained mechanical lifting effect and histological revitalization through the stimulation of fibroblasts to produce collagen, hyaluronic acid, and elastin. This approach is preferred by patients seeking to avoid invasive surgery due to its enhanced safety profile, minimal downtime, and lack of visible scarring, while still achieving early and long-lasting aesthetic improvements.