Mental health is a paramount concern in contemporary urban environments, necessitating comprehensive approaches to understanding its determinants and formulating effective interventions. This research project adopts a multifaceted methodology to explore the factors influencing mental well-being in urban areas, specifically focusing on cities within Gujarat. By integrating Geographic Information Systems (GIS) technology and predictive modeling techniques, we analyze various socio-environmental factors spanning air quality, noise pollution, green space availability, educational attainment, population density, income levels, and employability. At the same time, the GIS approach encompasses all major cities across India, the Random Forest algorithm is tailored specifically to the cities of Gujarat, reflecting the unique socio-geographical context of the region. Through rigorous data analysis and visualization, we identify spatial patterns and correlations, enabling the identification of areas most vulnerable to mental health challenges and prioritizing targeted interventions. This work presents our research's methodology, findings, and implications, offering valuable insights for policymakers and stakeholders striving to cultivate safe and supportive urban environments conducive to optimal mental health outcomes.