Partitiviruses, members of the Partitiviridae family, are persistent viruses that infect plants and maintain coexistence without causing observable symptoms. These viruses have segmented genomes, often bisegmented, with two separately encapsidated dsRNA segments (Buck and Kempson-Jones 1973). They infect a wide range of plants, including vegetables, fruits, and wild species, and are transmitted primarily through seeds at a high frequency (80–100%) (Boccardo et al. 1987). Partitiviruses are widespread in various organisms, including fungi, protozoa, gymnosperms, and algae (Veliceasa et al. 2006; Koga et al. 2003). Despite their low concentration in infected plants, they are present in all plant cells and are distributed through cell division, not plasmodesmata (Szego et al. 2006). The general characteristics of the family Partitiviridae are provided in Table 11.1.