High angular resolution diffusion-weighted imaging (HARDW) is a promising imaging method that allows for noninvasive assessment of intra-axonal diffusion anisotropy. HARDW can measure the degree of water diffusion anisotropy in white count number fibers by measuring the fractional displacement of water molecules in axons and other nervous tissue systems over time. This novel method can screen hanging spatial profiles of intra-axonal diffusion anisotropy, providing an unheard-of degree of element for evaluating white damage or neurodegenerative approaches. HARDW permits for dependable quantification of anisotropic diffusion in first-rate axons using multiple gradient instructions and a tight temporal decision. The accuracy of HARDW in figuring out anisotropic diffusion styles and the capability to spatially map them is critical to better apprehend the anatomical and physiological organization of white dependents and to correctly diagnose tissue harm.