In response to the problem of multiple composite vibration physical fields caused by high-speed rotation of fans on hard drive disk, this paper conducts in-depth research using testing and simulation methods, and optimizes vibration reduction design from the perspectives of chassis, airflow field, fans, etc. The main conclusions are as follows: 1. the optimal distance between the fan and the hard drive is 70 mm. 2. among the many optimization measures, adding honeycomb mesh and sound-absorbing foam have the most significant effect, which can improve the performance of hard drives by about 15%. This study plays an important guiding role in server architecture design, effectively guiding the RV vibration reduction design of mechanical hard disk configuration models, minimizing the vibration impact of high-speed rotating fans on the hard disk, and improving system vibration resistance and stability.