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Neonatal jaundice requires careful monitoring and management to prevent complications. Outpatient follow-up should assess feeding, weight, and signs of worsening jaundice. Phototherapy is discontinued when bilirubin levels are below 257μmol/L; TSB is rechecked after 24hours. Exchange transfusion is indicated for severe or rapidly rising bilirubin levels. Prevention includes maternal Rh screening, Coombs testing, and prophylactic anti-D immunoglobulin. Daily TcB screening using the Bhutani nomogram guides risk stratification. Early phototherapy is considered for Coombs-positive infants. Frequent breastfeeding (8–12 times/day) is encouraged, and formula supplementation may be needed for poor intake or dehydration, with specialist referral when necessary.

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Neonatal Hyperbilirubinemia

  • 章节

  • 发表日期：

    2025年

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  • Kow Wey Jet,
  • Yogarabindranath Swarna Nantha

摘要

Neonatal jaundice requires careful monitoring and management to prevent complications. Outpatient follow-up should assess feeding, weight, and signs of worsening jaundice. Phototherapy is discontinued when bilirubin levels are below 257μmol/L; TSB is rechecked after 24hours. Exchange transfusion is indicated for severe or rapidly rising bilirubin levels. Prevention includes maternal Rh screening, Coombs testing, and prophylactic anti-D immunoglobulin. Daily TcB screening using the Bhutani nomogram guides risk stratification. Early phototherapy is considered for Coombs-positive infants. Frequent breastfeeding (8–12 times/day) is encouraged, and formula supplementation may be needed for poor intake or dehydration, with specialist referral when necessary.