Currently, e-waste is growing exponentially, because of the continuous consumer requirements and fast advancements in technology. These are usually buried untreated or burned in the open environment without any caution. The non-biodegradable nature of e-waste makes its proper remediation more important. The components of e-waste are metals, halogens, refractory oxides, and plastic which are hazardous to the health of living beings and the biosphere. The metal and toxic components of e-waste can leach out and harm the environment in terms of pollution in soil and water and eventually accumulate in the food chain eventually reaching human beings. Despite the environmental concerns, e-waste is also a prominent secondary metal source, which makes their recycling industrially beneficial. Some conventional methods used for their recycling are hydrometallurgy and pyrometallurgy, but these methods require high cost and energy. They also produce toxic gases and harmful chemicals in the process. Biological methods can become a great alternative to conventional methods because they are cost and energy-efficient compared with hydrometallurgy and pyrometallurgy. Bioleaching is a method that uses bacterial and fungal species to leach out metals from e-waste. Bioleaching has the potential to be applied industrially for the leaching of metals.