The precast building is ideally suited for mass housing projects because of its fast construction. While precast construction is popular worldwide, it has not gained popularity in India. Very limited research has been conducted on this topic among Indian researchers. In the present paper, the seismic analysis of a 10-story precast building frame is presented. Beam and column elements are precast in a way such that they can be connected in situ. The connections considered for the present analysis are wet-type connections that require specific reinforcement detailing. The study is performed with three types of modeling, namely, (i) a link with a specified property at the beam-column junction and a link showing the inelastic behavior of the beam at section 0.1l  (l = length of the beam) from the center of the column, (ii) only a link provided at the beam-column junction, and (iii) a link at the beam-column junction and default plastic hinge (available in SAP2000) at 0.1l distance from the center of the column. The segment from the center of the column to the connection link is assumed to be rigid. In order to compare the behavior of the precast system, the same frame with a monolithic connection is analyzed. The moment–rotation curves of the monolithic connection and precast connection (link) are taken from the available literature. The response quantities of interest include peak top floor displacement, maximum inter-story drift (floors), maximum base shear, and maximum absolute acceleration (story). The responses are obtained by non-linear time history analysis using SAP2000 for a far-field earthquake. A range of peak ground acceleration levels starting from 0.2 to 0.6 g is considered in the analysis. Responses of the frame with different types of modeling of the precast system and the monolithic connection are compared in order to illustrate the seismic behavior of the precast building frame.