On conventional railways, it is standard practice to install CWR turnouts on bridges, leading to the establishment of well-defined standard design drawings for turnout girders in such systems. Typically, the turnout girders in these railways are constructed as ordinary reinforced concrete simply-supported T-girders, with a top width of either 1.6 or 1.7 m and a span ranging from 12 to 32 m. However, the design of CWR turnout girders on high-speed railways is currently confronted with new challenges. Specifically, there is a need for tailor-made bridge arrangements that integrate seamlessly with the turnouts. Accommodating the considerable width variations in the station throat area poses an additional design challenge for the bridge structure. Moreover, it is crucial to specifically study and rationally design the arrangements of longitudinal and transverse bearings for the turnout girders. The design of the bridge substructures presents its own set of challenges, particularly in addressing the significant longitudinal forces exerted by the CWR turnouts on the bridges. This chapter focuses on the study of turnout girders on high-speed railways, such as the fundamental principles governing the layout of turnouts and bridges, span arrangements, shear lag effects, and live load amplification coefficient. These analyses aim to effectively tackle the aforementioned challenges within the context of the Beijing–Shanghai High-Speed Railway.