A reliability-based design and analysis of reinforced anchors for transmission tower foundations  is presented using the Kriging-based response surface method. The improvement of the uplift capacity of anchors in reinforced soil is demonstrated using a three-dimensional numerical model. The initial design of the anchor plate is based on the uplift forces exerted at the foundation of a typical tower subjected to lateral wind forces. Next, a Kriging metamodel is constructed to predict the uplift capacity of anchors in unreinforced and reinforced soils to conduct reliability-based analysis considering the random nature of the uplift load, soil properties, and reinforcement stiffness. The mean uplift capacity of the anchor at 15% uplift displacement is increased by 1.35 times in the presence of reinforcement on the top of the foundation. The probabilistic analysis results indicate that the failure probability of the foundation in reinforced soil reduces significantly for the uplift forces obtained at the transmission tower foundation level. The influence of the variability of different load and resistance parameters on the stability of the foundation is examined. The variation of the reliability index with the factor of safety is presented, and the limitations of the conventional safety factor approach are discussed.