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In surgical pathology, an understanding of the normal ovarian anatomy and the range of nonneoplastic reactive, inflammatory, and infectious conditions of the ovary is essential during the examination of gynecological specimens. Pathologists routinely evaluate nonneoplastic adult ovaries as components of (1) hysterectomy procedures for uterine leiomyomata, uterine prolapse, vaginal bleeding, or gynecological cancer and (2) risk-reducing prophylactic salpingo-oophorectomy, with the primary goals of excluding ovarian malignancy and/or determining whether the ovary is the source of hormone production driving uterine cancer. In these scenarios, with the exception of endometriosis, ovarian infection, or a hormone-producing lesion, any incidental nonneoplastic lesion encountered in the ovary is likely not of clinical significance. However, it is important for the pathologist to be able to recognize various benign normal structures, inflammatory conditions, and infectious conditions within the ovary.

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Normal Structure and Function, Inflammatory and Other Miscellaneous Lesions of the Ovary

  • 工具书词条

  • 发表日期：

    2025年

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  • David Suster,
  • Robert Ta,
  • Catherine Connolly,
  • Douglas I. Lin

摘要

In surgical pathology, an understanding of the normal ovarian anatomy and the range of nonneoplastic reactive, inflammatory, and infectious conditions of the ovary is essential during the examination of gynecological specimens. Pathologists routinely evaluate nonneoplastic adult ovaries as components of (1) hysterectomy procedures for uterine leiomyomata, uterine prolapse, vaginal bleeding, or gynecological cancer and (2) risk-reducing prophylactic salpingo-oophorectomy, with the primary goals of excluding ovarian malignancy and/or determining whether the ovary is the source of hormone production driving uterine cancer. In these scenarios, with the exception of endometriosis, ovarian infection, or a hormone-producing lesion, any incidental nonneoplastic lesion encountered in the ovary is likely not of clinical significance. However, it is important for the pathologist to be able to recognize various benign normal structures, inflammatory conditions, and infectious conditions within the ovary.