Acid Mine Drainage (AMD) is a persistent environmental challenge that results from mining activities, leading to the contamination of water bodies and subsequent ecological and public health risks. Constructed wetlands have emerged as a promising approach for AMD treatment due to their potential to mimic natural processes and effectively remove pollutants. This study focuses on assessing the treatment performance of a specially designed three-chamber constructed wetland system for synthetic AMD. Two systems of constructed wetland were adopted in the study, one was kept unplanted and one was planted with Alocasia odora (Elephant Ears). The investigation evaluates the removal efficiency of a range of physical and chemical parameters and delves into the effectiveness of the system in removing key elements such as iron (Fe), aluminium (Al), and manganese (Mn) on top of BOD, COD  and \({\text{SO}}_{4}^{2-}\) The study adopts various hydraulic retention times (HRTs) to analyze their impact on treatment efficiency. Results showed good removal efficiency of the pollutants by the pilot-scale constructed wetland system. The removal efficiencies of Fe, Al and Mn were found to be 94%, 60% and 45%, respectively, and of BOD, COD, and \({\text{SO}}_{4}^{2-}\) were found to be 85%, 72%, and 56% in the system planted with Alocasia odora (Elephant Ears) as compared to the one kept unplanted which showed removal efficiencies of 84%, 48% and 36% for Fe, Al and Mn, respectively and 88, 75, and 42% for BOD, COD, and \({\text{SO}}_{4}^{2-}\) .