Metal-organic frameworks (MOFs) are a class of crystalline porous materials which are distinguished by their high surface areas, chemical stability, and adjustable pore widths. A subclass of environmental functional materials known as stimulus responsive MOF materials are widely used in many frontier sectors because of their unique structure, abundantly available activity sites, and reversible physicochemical properties. Materials that show low emission in diluted fluids, but spectacular emission when aggregated or solid, are known as aggregation-induced emission (AIE) materials. AIE luminogens (AIEgens) are particularly promising for a variety of applications because, in the aggregate state, they have significant advantages over traditional luminous materials, such as high quantum yield, great photostability, and minimal background signals. AIEgens can be integrated into designable MOFs to create tunable and well-ordered AIE materials. This permits more in-depth investigation of AIE processes and exact control over photophysical properties. Because AIE-modified MOFs can change their properties in response to external stimuli, there has been interest in using them as stimuli-responsive sensors. When paired with functionalization strategies like aptamer integration, their adaptability to a wide range of external stimuli makes them ideal for use in biosensing, drug delivery, environmental monitoring, and optical sensing. This chapter explores the synthesis, characterization, and functional applications of AIE-active MOFs, with a focus on their performance in detecting environmental changes and chemical stimuli.