Health promotion is a core component of public health, dedicated to empowering individuals and communities to enhance their health and overall well-being. It involves a range of strategies, including behavior change, education, and policymaking, designed to prevent illness and improve quality of life. Health promotion is closely linked with health education and health literacy. Health education equips individuals with the knowledge and skills necessary to understand and apply health information, an essential step in developing health literacy. In turn, higher levels of health literacy enable individuals to make informed decisions, adopt healthier lifestyles, and navigate health systems more effectively. Health promotion integrates both health education and the cultivation of health literacy to empower people and communities to take charge of their health and to foster environments that support well-being. This chapter begins by exploring the key principles, strategies, and challenges associated with health promotion, highlighting its relevance in contemporary society. It then examines the Ottawa Charter as a guiding framework, outlining its role in shaping global health promotion efforts. The chapter concludes by addressing the relationship between health literacy and health education, along with the challenges they present in the pursuit of effective health promotion. Achieving the goal of health promotion requires collective action from governments, healthcare providers, and individuals, working together to ensure that health and well-being are within reach for all.