Active-matrix organic light-emitting diodes (AMOLEDs) present big challenge to liquid crystal displays (LCDs). However the illumination efficiency of an AMOLED heavily depends on temperature. The accurate temperature distribution is important for implementing compensation of AMOLED panel to improve display uniformity. With the increase of size and resolution, the voltage drop (IR-drop) caused by the resistance of the power supply line can’t be ignored, which also has influence on temperature distribution. The paper proposes a temperature distribution analysis method based on IR-drop. Firstly, sparse-representation-based IR-drop model is put forward, which can help solve IR-drop of AMOLED with high resolution. Secondly, the paper introduces IR-drop based heat power model, which can help perform the temperature simulation. Finally, the temperature distribution of the AMOLED panel is obtained by finite element analysis. The temperature measurements are performed on a 27inch 4K AMOLED panel to validate the proposed method. The simulation results are in good agreement with the actual measurements, which means the analysis method proposed in this paper presents high accuracy and high practicability.