The green technology innovation level of manufacturing enterprises is crucial to the development of enterprises and the maintenance of competitive advantages. How to realize the high green technology innovation of manufacturing enterprises is an urgent problem to be solved. This paper takes 67 manufacturing enterprises as the research object. Using the QCA method, this study analyzed 67 manufacturing enterprises and identified six configurations that significantly impact green technology innovation. The research found that the enterprise has 6 kinds of configuration to achieve high and high green technology innovation, which are divided into three types, respectively, the dual drive of market responsibility and public responsibility, green output and product consumption drive and green input product production and information disclosure drive. The results show that green input and product production, green output and product consumption, employee responsibility, market responsibility, public responsibility, equity governance, information disclosure and technological innovation are not the necessary conditions for enterprises to realize high-green technology innovation, but they have an important impact on the high-green technology innovation of enterprises. This paper provides new insights for the realization path of high green technology innovation, and also provides useful inspiration for manufacturing enterprises to realize high green technology innovation.