Identification of nucleic acids needs certificated positive samples for quality control, and reference materials (RMs) are developing to be received by most researchers in molecular biology. However, uniformity and disharmonization exist in the production and regulation of reference materials between different organizations. The objective of this chapter is to review and clarify the definition, attributes and applications, and common regulation process of reference materials in the context of nucleic acid identification.

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Reference Materials: A Golden Criterion in Nucleic Acid Identification

  • Wentao Xu

摘要

Identification of nucleic acids needs certificated positive samples for quality control, and reference materials (RMs) are developing to be received by most researchers in molecular biology. However, uniformity and disharmonization exist in the production and regulation of reference materials between different organizations. The objective of this chapter is to review and clarify the definition, attributes and applications, and common regulation process of reference materials in the context of nucleic acid identification.