This chapter explores Australia’s critical minerals supply chain, emphasizing the need to balance security, sustainability, and economic viability—a challenge known as the mineral trilemma. Australia plays a significant role due to its vast reserves and stable political environment, with global demand for critical minerals such as lithium, nickel, cobalt, and rare earth elements rising, driven by technological advancements and renewable energy demands. However, the country faces challenges related to environmental and social governance, geopolitical dependencies, and economic distribution. The chapter analyses each stage of the supply chain, from upstream extraction and processing to downstream market distribution, highlighting Australia’s strategies and policies to navigate these complexities. The discussion includes Australia’s engagement in international partnerships, its focus on sustainable practices, and the integration of Indigenous perspectives in mining operations. The chapter concludes by offering policy recommendations to enhance Australia’s position as a global leader in the critical minerals sector, emphasizing the importance of a balanced, holistic approach to managing the mineral trilemma. Australia must adapt to the rapid evolution of global demand for critical minerals in the future by embracing technological innovation, enhancing sustainability, and forging resilient international partnerships. This will ensure its long-term competitiveness and leadership in the global critical minerals landscape.