This chapter delves into the significance of using remote sensing technologies to monitor and assess the changes in hydrology and water resources in the Hindu Kush-Himalayan (HKH) region. As one of the most ecologically sensitive areas on the planet, the HKH is home to vast glaciers, snowfields, and permafrost, which are crucial for the region’s water resources and ecosystems. The rapid environmental changes driven by climate change and human activities have profound impacts on these natural resources, necessitating scientific monitoring and evaluation to better understand their dynamics.