For reliable food supply, efficient supply chain is highly desirable. In times where Industry 4.0-based digital technologies help increase efficiency of all industrial processes, food supply chain (FSC) is no different. This paper involves discussing the aspects of food supply chain and how implementing digital technologies can help overcome the existing loopholes in the FSC. Authors have a carried out a systematic literature review to study the Industry 4.0-based digital technologies and its implementation challenges in the FSC. The paper aims to analyse these challenges using Best Worst Method (BWM), which includes survey design and analysis of responses from field experts to rank the challenges. The outcome of the paper is the ranking and analysis of identified challenges. Authors observed that Insufficient technical knowledge/lack of skilled workforce for implementing technology (0.1609), Management decisions/Organisation policies (0.1422) and Interoperability and Integration between different technology models (0.1295) are top three challenges. Finding of current study can assist the FSC in the prioritise addressal of issues in the implementation of Industry 4.0 digital technologies, therefore maximising the efficiency of FSC and customer satisfaction.