Obsessive-compulsive disorder (OCD) is a prevalent and debilitating psychiatric condition that profoundly impacts individuals’ lives. Its complex and multifactorial etiology presents significant challenges for effective treatment. While many patients benefit from standard interventions such as pharmacological therapies and psychotherapy, a substantial number remain resistant to treatment, resulting in poor long-term outcomes. Emerging neurostimulation therapies, encompassing both noninvasive and invasive techniques, offer promising alternatives for managing OCD. Numerous clinical trials have explored novel neurostimulation protocols, aiming to improve treatment efficacy. However, findings remain inconsistent, and no universally accepted approach has been established. This underscores the critical need for further research to refine stimulation parameters and identify factors that influence individual responsiveness to these interventions. This chapter provides a comprehensive overview of neuromodulation strategies for OCD, highlighting current advancements, ongoing challenges, and future directions in this rapidly evolving field.