Bipolar Disorder
摘要
Bipolar disorder constitutes a substantial source of personal distress and economic burden, as evidenced by the Global Burden of Disease Study. Conventional therapeutic strategies, including pharmacotherapy and psychotherapy, are endorsed by clinical guidelines and expert consensus. However, a significant proportion of individuals with bipolar disorder exhibit inadequate treatment responses or develop treatment resistance, necessitating alternative or adjunctive interventions. Over the past two decades, various neuromodulatory techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), have been investigated to address the complexities of bipolar disorder, leading to increased interest in their therapeutic applications. This chapter provides an overview of advanced TMS and tDCS paradigms in the context of bipolar disorder.