Heat exchanger is the primary device in the industries where heat transfer is a predominant process. It is a onetime cost equipment and also is durable for longer period of time, thus making it viable for the mass manufacturing industries. The new demanding criteria in this sector have led to many new types of development in heat exchangers. The current research related to the investigations of heat exchange among three fluids, which are at distinct temperatures. An innovative triple coextensive tubular heat exchanger with materials brass, copper, and PVC for inner, middle, and outer pipes having 30 mm, 60 mm, 90 mm diameter, respectively, is used for experimentation. The heat exchanger is premeditated and fabricated for investigation. Three fluids such as normal, hot, and cold water are taken for the investigation. Several flow arrangements are deliberated for the investigations with assorted mass flow rates. Further, the cold water is replaced by two distinct water-based nanofluids such as Al2O3 and TiO2 nanoparticles and compared with the cold-water configuration. The nanofluids are used for investigation are at various weight concentration such as 0.01, 0.03, 0.05, and 0.07wt%. The focus of the current analysis is to improve the heat exchange ability of concentric heat exchanger using nanofluids. As the heat pipes play a vital role in heat exchanger so an amalgamation of clear acrylic and brass is used as outer and inner material, respectively. The temperature distribution pertaining to the various fluids lengthwise of the tube is measured experimentally with the help of K-type thermocouple for the different flow arrangements. The steady state temperatures are recorded by the help of a Chinos data acquisition system. The effectiveness of the heat exchanger is reckoned for every of the layouts and assessed. The results show that heat exchanger effectiveness is superior for nanofluids as compared to normal water.