This chapter deals with the practical details of how to design and implement a Delphi study. It covers setting an aim, selecting an expert panel, determining panel size, minimizing panel drop-out, constructing a questionnaire, providing additional evidence to panel members, piloting a questionnaire, providing feedback to the panel, defining consensus, deciding number of rounds, software for running Delphi studies, reporting Delphi studies, assessing the quality of Delphi studies and study pre-registration.