In emergency scenarios, such as natural disasters or public health crises, the prompt and effective transportation of multiple loads to different destinations emerges as a crucial element of a well-coordinated response. This study delves into the logistical challenges of transportation planning, addressing the compatibility of various load types among themselves, and with the aircraft in a one-to-many and many-to-one transportation network (1-M/M-1). The investigation encompasses fleet selection, cargo loading, routing, and the efficient utilization of available cargo aircraft. The proposed model finds application in scenarios like military movements during crises and humanitarian missions, offering a strategic approach to plan the transportation of sensitive cargo, equipment, and supplies. The paper outlines vital facets of emergency transportation, supported by illustrative examples and the computational performance of the solver on a smaller-scale problem. Through a comparative analysis of load compatibility issues, the study provides valuable insights into how the model can optimize the logistics of emergency response efforts, ensuring the timely and efficient delivery of essential resources to critical locations.