The interplay between emerging pollutants and climate change presents unprecedented ecological challenges, necessitating a comprehensive understanding and innovative solutions. This chapter provides a detailed overview of the ecological impacts of emerging pollutants and industrial chemicals within the framework of a changing climate. The novelty of this work lies in its integrative strategy, examining not only the direct effects of these pollutants on ecosystems but also their interactions with climate change-induced stressors such as increased temperatures and altered precipitation patterns. This chapter further explores the mechanisms through which emerging pollutants exacerbate climate change impacts on biodiversity, water quality, and ecosystem functioning. By synthesizing recent research, it highlights the synergistic effects that magnify ecological risks, leading to reduced resilience of ecosystems. Furthermore, it focuses on developing adaptive and mitigative strategies tailored to the dynamic nature of both emerging pollutants and climate change. This includes advanced monitoring techniques and the application of nature-based solutions to enhance ecosystem resilience. Additionally, it also addresses policy and regulatory challenges, advocating for integrated environmental management practices that consider the dual threats of pollution and climate change. Moreover, it underscores the value of interdisciplinary collaboration and stakeholder engagement in crafting effective solutions. By providing a forward-looking perspective, this chapter’s overall objective is to contribute to the global discourse on ecological sustainability, offering insights and practical approaches to mitigate the ecological effects of emerging pollutants in the face of climate change.