Infratentorial Pediatric Brain Tumors
摘要
Infratentorial or posterior fossa tumors predominate in children after the age of 3–4 years, and account for more than 50% of brain tumors. The most common presentation in children is symptomatic elevated intracranial pressure (ICP) like headache secondary to obstructive hydrocephalus. Symptoms also depend on age of presentation. Infants may present with macrocrania, drowsiness, nausea, and vomiting. Truncal and gait ataxia, tinnitus is seen more often in older children. Common intra-axial posterior fossa tumors include medulloblastoma, pilocytic astrocytoma, ependymoma, atypical teratoid-rhabdoid tumor (ATRT), brainstem glioma, and rarely teratoma. Cerebellar hemangioblastoma may be seen in the context of Von Hippel-Lindau (VHL) disease but otherwise it is rare. Extra-axial tumors are infrequently encountered, and include dermoid, epidermoid, enterogenous cyst, teratoma, schwannoma, meningioma, and skull base tumors.