This chapter focuses on the profound impact of regional conflicts on mental health within South Asia, a region marred by decades of strife in countries like Afghanistan, Bangladesh, India, and Sri Lanka. These conflicts have led to a high prevalence of mental health disorders such as post-traumatic stress disorder (PTSD), depression, and substance abuse, significantly affecting the well-being of the population. This chapter highlights the psychological and social consequences, including refugee crises, community breakdown, and intergenerational trauma, with specific risks to women, children, and ethnic/religious minorities. Cultural and systemic barriers to mental healthcare, such as stigma, inequitable resource allocation, and workforce shortages, are also discussed. While local and international initiatives have attempted to address these issues through community-based programs and partnerships, significant gaps remain. The chapter advocates for strengthening mental health structures through training, increased funding, and collaborative research. It also emphasizes the importance of peacebuilding to foster cooperation, respect, and moral courage, ultimately improving mental health outcomes in the region.