In recent years, trying to define, measure, and improve the well-being of students and teachers has become a subject that has attracted the attention of researchers worldwide. Although well-being is a universal phenomenon, the well-being of students and teachers living in Asian and European communities is affected by many different cultural factors. Moreover, as a bridge between Asian and European countries due to its geographical location, Türkiye also has the unique importance of discovering various cultural effects on well-being. Thus, this discussion chapter delves into recent studies on student and teacher well-being in Türkiye, examining them through Bronfenbrenner’s ecological system theory and Türkiye's distinctive features on Hofstede’s cultural dimensions. Türkiye is culturally heterogeneous in that it has structured its public bureaucracy and educational institutions by European culture, even though it has similar characteristics to Asian cultures, and this in-betweenness has multifaceted effects on teacher and student well-being. With its unique cultural and ecological situation, the Türkiye case provides insightful inspiration and resources for addressing well-being issues in a multicultural global context.