The tendency of the building industry to use sustainable components is becoming more and more widespread to produce more ecologically friendly concrete. Furthermore, current studies are carried out on numerous new substitutes and alterna- tives, in which economic viability and performance are considered important. This study provides a thorough assessment of the strength properties of microsilica-based concrete. Studies were carried out to use microsilica materials in varied proportions from 0–50% in M20 Grade of Concrete. When compared to a convention- al mix of concrete, Microsilica ingredients help concrete to achieve high strength at an early stage and have greater durability and workability. The curing was done for 7, 14, 28, 56, and 90 days. The mechanical properties of the microsilica concrete were determined by performing compressive strength test, modulus of elasticity test, and flexural strength test of concrete. In addition to mechanical properties, durability studies specifically focusing on acid resistance and alkaline resistance were conducted to examine the chemical resistance of microsilica-based concrete. As a result, it can be concluded from the study that using microsilica as a partial replacement of cement has the twin advantage of being an eco-friendly material that lowers carbon emissions while also improving workability and mechanical strength of concrete. The optimum result was found at 20% replacement of cement using microsilica.