This chapter explores the realm of research ethics in longitudinal research. Particular attention will be paid to research settings where the research site is a small community. Ethical questions are always present at all levels when conducting qualitative longitudinal research. Yet in small rural communities where all young people know each other, it is particularly challenging to preserve the participants’ anonymity. Moreover, in a long research relationship, sensitive issues regarding young people’s health and social relationships as well as their losses and sorrows are discussed. In a research relationship with a young person, the researcher carries extra responsibilities because young people are more vulnerable and less aware of what the consequences are if they disclose sensitive information. Thus, researchers within longitudinal qualitative studies must both be sensitive to what subjects have revealed during the research encounters as well as what to disclose in analysis, academic papers, and, thus, to the public. Thus, the chapter argues for relational research ethics, which are based on everyday experiences and emphasise reciprocal relationships, recognition, and responsiveness towards the research participants. The chapter draws on experiences from a Finnish qualitative follow-up, Youth in Time, which has involved approximately 100 young people (born in the year 2000) from five different regions around Finland, including young people from rural environments.