This chapter discusses the aspects of spiritual happiness reflected in John Keats’s poetry. It examines the study by providing insights into how Keats’s poetry combines the knowledge of medicine and literature with a thorough understanding of spiritual elements. The study employs the library method to unravel the elements of spiritual happiness portrayed in John Keats’s selected works. It further explores spiritual happiness enshrined in those works of poetry, which can help people explore spiritual solutions to today’s complex world. It concludes that spirituality must be thoroughly studied in a complex world marked by numerous conflicts in line with the other fields for holistic happiness. Scholars must also research other forms of literature apart from poetry to discover possible solutions to their everyday problems. The study also suggests that meditation can help people delve into the different areas of the mind and explore the hidden space, creating immense transformations in the universe in the long run.