Pectin is a natural polysaccharide found in plant cell walls and has been widely studied as a biomaterial for various applications because of its biocompatible nature, low toxicity, and biodegradability. Furthermore, pectin-based nanobiohybrids have gained too much attention for their potential use in heavy metal removal from aquatic environments. As pectin has ability form hydrogels which can encapsulate target metal ions. Further, the addition of nanoparticle increases its efficiency by increasing surface area and binding sites. The binding capacity, selectivity and reusability used as factors for determining the effectiveness of these nanohybrids for the removal of heavy metal ions. Furthermore, the mechanism of nanobiohybrids involved in the removal of heavy metals such as chelation, electrostatic attraction, and ion exchange have been discussed in detail. This chapter has also provided a detail overview on the development and applications areas of pectin-based Nanocomposites particularly, for the removal of heavy metals and their ions. In the start of chapter, the properties of pectin and their interaction with heavy metals is given. In the next section, the synthesis and characterization of pectin-based nanohybrids with different modifications have been represented including incorporated 2D nanomaterials and metal oxides. The utilization of pectin nanobiohybrids for the selective capping of heavy metals is advantageous over traditional methods, like chemical adsorption and precipitation. Additionally, the pectin is a natural, easy accessible, economical, and a biodegradable material which make it reliable in modern scientific community. Consequently, the usage of nanobiohybrids such as pectin for heavy metal removal could increases selectivity and efficiency of process along with less secondary waste generation into the ecosystem and considered as a greener approach.