The escalating global population has driven an increase in vehicle numbers, raising fuel demand and environmental concerns [8]. To address this, there is growing interest in alternative fuels like ethanol, derived from plant sugars such as sugarcane, corn, and wheat [6]. Ethanol is lauded for its renewable nature, cost-effectiveness, and clean-burning characteristics, which help reduce vehicle emissions [12]. In India, ethanol production not only benefits the environment but also boosts employment and supports agricultural growth. Recent milestones include the unveiling of the world's first BS-VI Stage II Electrified Flex Fuel Vehicle and the launch of the Global Biofuel Alliance during the G20 summit, showcasing international collaboration in biofuel innovation [1]. The paper examines the historical context of ethanol-based vehicles, global ethanol production trends, India's growing ethanol sector, production techniques, and challenges associated with flex-fuel vehicles. It also proposes a supply chain model aimed at optimizing ethanol production by ensuring a consistent supply of raw materials, benefiting both farmers and industrialists. This model aligns with Sustainable Development Goals (SDGs) by promoting sustainable energy sources, supporting economic growth, and advancing climate action through the adoption of ethanol as a renewable fuel. Ultimately, this supply chain model is crucial for advancing sustainable development objectives and fostering a brighter future for all stakeholders involved.