Tropane alkaloids are known to exist in plants such as those belonging to Solanaceae, Convolvulaceae, Erythroxylaceae, Brassicaceae, Euphorbiaceae, Rhizophoraceae, Moraceae, and Proteaceae. This chapter provides information on the plant sources of these alkaloids and the distribution of these plants. The valid and accepted names have been obtained from Plants of the World Online. Additionally, the text includes information on the tropane alkaloids found in different species.