Social entrepreneurship to be successful requires effective leadership. This chapter will discuss the role of leadership in social entrepreneurship by focusing on different types such as entrepreneurial, female, charismatic, authentic, transformational, maverick, diplomatic, moral, ethical, compassionate and community. As there are a diverse range of leadership activities conducted by social entrepreneurs so it helps to take a holistic approach. This will enable a better understanding about the role of context in social entrepreneurship and how healthy leadership activities can facilitate change.