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Young male, height 175 cm, no comorbid conditions, and rapidly worsening respiratory failure. Chest X-ray: bilateral opacities. No other organ involvement. On controlled mechanical ventilation. Vt 420 ml, FiO2–1.0, PEEP 15 cm H2O, Pplat 30 cm H2O (under paralysis). ABG analysis shows PO2 55 mm Hg, PCO2 79 mm Hg, pH 7.17, HCO3 28. How do we proceed??

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Management of Refractory Hypoxemia in Acute Respiratory Distress Syndrome

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  • 发表日期：

    2025年

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  • Sameer Jog,
  • Prasanna Marudwar,
  • Giacomo Grasselli

摘要

Young male, height 175 cm, no comorbid conditions, and rapidly worsening respiratory failure. Chest X-ray: bilateral opacities. No other organ involvement. On controlled mechanical ventilation. Vt 420 ml, FiO2–1.0, PEEP 15 cm H2O, Pplat 30 cm H2O (under paralysis). ABG analysis shows PO2 55 mm Hg, PCO2 79 mm Hg, pH 7.17, HCO3 28. How do we proceed??