Nano-enhanced hydration is a novel method in sports nutrition that integrates nanoparticles to improve hydration. Hydration plays the most significant role in sports nutrition, affecting physical performance, overall healthHealth and recovery by helping transport oxygen and nutrients to cells, removing waste from cells and regulating bodyBody temperature. Incorporating nanotechnology in hydration can help in faster absorptionAbsorption of nutrients, targeted cellular hydration and electrolyteElectrolytes management. For example, encapsulation of essential nutrients in nano-emulsions or lipid nanoparticles aids in the targeted deliveryTargeted delivery (liposomes, polymeric nanoparticles) of nutrients to a specific cell or tissue and increases the bioavailability. Therefore, nanoparticle-enhanced hydration will be much more effective than the traditional hydration methods. This chapter discusses about the science behind nano-enhanced hydration, discussing its role in overcoming dehydration, supporting thermoregulation during high-intensity activities and maintaining optimal osmotic balanceBalance. Emerging studies highlight the efficiencyEfficiency of nano-structured water moleculesMolecules by incorporating nano-emulsions and lipid nanoparticles, which improving intercellular hydration compared to other conventional methods. Nano-enhanced hydration stands as a revolutionary developmentDevelopment, which offers athletes to achieve peak physical performance by combining sports nutrition with cutting edge nanoscience. The chapter further explores the evidence-based insights on nano-enhanced hydration for improving endurance, recovery and overall performance.