This chapter proposes a theoretical and methodological framework, accompanied with concrete analytical tools, that allow opening the “black box” of processes of working / non-working of technologies to inform conceptual frameworks with greater degrees of descriptive and explanatory capacity. This article synthesizes some of the theoretical-conceptual developments of a group of researchers from the Institute of Studies on Science and Technology of the National University of Quilmes (IESCT-UNQ-CIC-BA) in Argentina, whose result was the production of a relativist-constructivist framework: “Socio-Technical Analysis” (STA). The argumentative line of this chapter responds to the following sequence. First, the common-sense constructions about technology are critically addressed and a new definition of our own is proposed. Secondly, SCOT’s contributions to the category of working are presented. Thirdly, a critical analysis of the proposals focused on the notion of “working” is carried out, evaluating the contributions and restrictions of Wiebe Bijker, conceptually triangulating with contributions from Actor-Network Theory (Bruno Latour and Michel Callon) and Large Technological Systems (Thomas Hughes). Fourth, a new set of analytical tools is developed, suitable for complementing, deepening, and overcoming the restrictions of the previously available conceptualizations. Finally, a new definition of “working” is proposed, useful for operationalizing empirical research on non-linear socio-technical processes of construction of working and non-working.