Aiming at the problems of high viscosity, low permeability of Shale oil, poor underground crude oil flow, and difficult implementation of water drive, chemical drive and other technologies, the recovery factor of Shale oil can be further improved by using air drive technology to supplement formation energy, reduce crude oil viscosity and thermal expansion. To clarify the changes of gas and oil production after low-temperature oxidation of Shale oil and air at different temperatures, this article conducted relevant experiments using self-developed equipment. The experimental results show that with the increase of oxidation temperature of Shale oil, its oxygen consumption rate gradually increases, the heavy components of the produced oil increase, the viscosity decreases, the concentration of free radicals gradually increases, and the g-factor gradually decreases, this indicates that the stability of oxidation products has been further improved; When the low-temperature oxidation temperature is higher than 250 °C, Shale oil can smoothly enter the later stage of low-temperature oxidation, which is the key to achieve stable combustion.