Optical tweezers can trap and manipulate particles with size ranging from nanometers to micrometers with tightly focused laser beams, serving as critical tools in many fields, such as biomedicine, physical chemistry, and materials science. The continuous development of optical beam shaping technology has revolutionized the optical manipulation technique, evolving from stable capture of particles with a point trap to versatile manipulation of particles using novel beams with unique phase, amplitude, and polarization distribution. Nowadays, the elaborately structured light fields facilitate the driving of particles along more complex trajectories, enhancing optical forces, and providing more degrees of freedom for manipulating objects. In this chapter, we will focus on the generation of typical novel beams and their applications in particle manipulation, aiming to highlight the significant advancements made in optical tweezers technology in recent years and inspire further research in related fields.