The textile industry has witnessed an upsurge in the use of enzymatic treatments since they are energy and environmentally efficient alternatives. The focus of biotechnology and enzyme modification advancements has been on several uses in textile processes. Key enzymes include amylases, used in both bleaching and desizing processes. Peroxidase, which also plays a role in these procedures, and cellulase, activated for denim finishing and bio-polishing. These enzymes provide environmentally acceptable and long-lasting substitutes for conventional chemical treatments. The textile industry can cut back on energy, water, and chemical waste by using enzymes. To accomplish environmental goals and achieve cleaner production processes, enzymes are essential. A sizeable share of the world's textile industry is made up of cellulosic textiles, and cleaning them frequently requires the use of harsh chemicals and a lot of energy, which raises environmental concerns. By efficiently using the catalytic power of enzymes to break down stains and dirt, enzymatic methods provide a sustainable substitute. This paper examines current developments in the creation and use of unique enzymes for cellulosic textile biotechnology cleaning. It includes new oxidative enzymes, hemicellulases, and cellulases from various fungal and microbial origins. These enzymes are highly suitable for industrial-scale textile cleaning procedures because of their increased stability, activity, and specificity. This study also focuses on the possible synergistic effects of different enzyme combinations for enhanced cleaning efficacy in cellulosic textile cleaning.