Lithium-ion batteries, as the sole energy source for electric vehicles, have a significant impact on battery capacity, cycle life, and safety due to their thermal characteristics. The direct cooling plate, as the mainstream heat exchange component of the LIB cooling system, directly affects the temperature of the lithium-ion batteries. In order to improve the performance of the thermal management system, the refrigerant direct cooling thermal management system was studied. Firstly, a direct cooling simulation model was established and verified. And, the results show that the error is less than 10%, which shows that this model is reasonable and credible. Through numerical simulation, different flow channel structures were designed to compare and study. The results show that the double-snake structure direct cooling plate with refrigerant inlets on the outer side shows the better comprehensive temperature and pressure performance than other structures. This research can provide technical support for the design of direct cooling systems.