Whole-Home Automation System (WHAS) has several constraints in intelligent experimental environment including complex physical environment, poor flexibility, high maintenance cost, resource limitation, lack of diversity in appliance and scenario, poor generalization performance of intelligent algorithm, and inability to provide heuristic ideas. We proposed HomeArena, a conceptual framework of multi-agent simulation for household appliance intelligence development and evaluation, and simulation process including modeling indoor environment, loading household appliance agent, lay outing sensors, building bionic agent, and performing automated simulation. We also discussed foundational design principles and implementation methods for various agents. Additionally, we also proposed a demo architecture of HomeArena, suggesting that a microkernel communication architecture based on ZeroMQ may be a satisfactory solution.