5G has substantially enhanced connectivity, with low latency and high data speed. QI and NLP may improve personalized sentiment analysis. This paper uses user profiles in 5G-enabled environments to improve sentiment analysis using QI and NLP. A novel framework that merges QI’s computing power with advanced NLP methods improves user-generated content analysis and interpretation. The framework leverages quantum algorithms to speed up sentiment analysis. Textual feelings are understood and classified using natural language processing methods. The system will feature user profiles to improve sentiment insights. The profiles include context-specific information on people’s interests, behaviors, and communication. Simulate numerous 5G-enabled communication settings to assess the proposed system’s performance. The foundation uses real-time data processing, dynamic user profile integration, and quantum-enhanced sentiment analysis algorithms. Future communication may be revolutionized by QI and NLP. Sentiment analysis outperforms other methods in accuracy and relevance. Quantum and NLP technologies will improve sentiment analysis, ushering in 5G’s powerful and personalized communication features. The study improved communication systems that are sensitive to user preferences and emotions.