Slip surface can significantly reduce the drag experienced on a stationary cylinder surface. The present numerical study is about the effect of slip on the rotating cylinder surface on vortex shedding within the laminar region for different Reynolds numbers. A domain of 50D \(\times \) 100D with structured quadrilateral grids which has 0.002D thickness of first layer around the cylinder considered for analysis in COMSOL Multiphysics 5.6 software by finite element method. Implicit scheme with backward difference formula used for the computation. Overall, the study highlights the influence of slip and rotation on the flow characteristics around a rotating cylinder, providing insights into the drag, lift, and vortex shedding behavior. The results indicate that slip has a positive effect on reducing drag, and the rotation of the cylinder further decreases drag. On the other hand, the presence of slip distribution leads to a decrease in lift despite an increase observed with rotation. The combined effect of rotation and slip distribution results in the re-appearance of vortex shedding at high rotation rates and increased slip distribution.