Aiming at the comprehensive decision-making problem of large-scale integration of rooftop photovoltaic into the power supply-guaranteed microgrid, a comprehensive evaluation method of rooftop photovoltaic grid-connected scheme based on analytic hierarchy process-entropy weight method-technique for order preference by similarity to ideal solution (TOPSIS) is proposed. Firstly, a comprehensive evaluation index system is constructed from the three dimensions of power grid side, user side and investment side. The power grid side pays attention to the impact of grid-connected operation, the user side considers priority and matching degree, and the investment side reflects construction costs and benefits. Secondly, the analytic hierarchy process and entropy weight method are used to obtain the main and guest weights of each index respectively, and the comprehensive weight is obtained based on the game combination weighting method. Then, the TOPSIS method is used to comprehensively score each roof photovoltaic construction scheme. Finally, the effectiveness of the proposed method is verified by an example of rooftop photovoltaic grid-connected scheme based on improved IEEE33 node system set up on MATLAB platform.