Since Seeman proposed using DNA as a nanomaterial, DNA Tile and DNA origami technologies have been successively proposed, and DNA has realized the programmable assembly from two-dimensional patterns to three-dimensional spatial structures. The nanostructures constructed by DNA have stable properties, regular geometric appearance, and spatial addressability, and are widely used in many fields. DNA algorithmic self-assembly can be realized by controlling the self-assembly process in ways such as sequence and connection rules. With the programmability of DNA sequences, the design of DNA nanostructures to realize DNA algorithmic self-assembly has made good progress. This chapter mainly includes DNA Tile computation, Turing equivalent Tile computation, programmable Tile structure, single-strand Tile (SST) computation, universal DNA Tile computation, DNA origami computation, etc.

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DNA Algorithmic Self-Assembly

  • Jin Xu

摘要

Since Seeman proposed using DNA as a nanomaterial, DNA Tile and DNA origami technologies have been successively proposed, and DNA has realized the programmable assembly from two-dimensional patterns to three-dimensional spatial structures. The nanostructures constructed by DNA have stable properties, regular geometric appearance, and spatial addressability, and are widely used in many fields. DNA algorithmic self-assembly can be realized by controlling the self-assembly process in ways such as sequence and connection rules. With the programmability of DNA sequences, the design of DNA nanostructures to realize DNA algorithmic self-assembly has made good progress. This chapter mainly includes DNA Tile computation, Turing equivalent Tile computation, programmable Tile structure, single-strand Tile (SST) computation, universal DNA Tile computation, DNA origami computation, etc.