Poly (vinylidene fluoride) membranes are widely used both in scientific research and industrial operation processes because of their outstanding properties, such as excellent thermal stability, great resistance to chemicals, and the ability to form membranes. However, PVDF membranes have one major problem: membrane wetting, which can lead to bacterial growth and pollution. This can be overcome if the pore size of the membrane is small, the porosity percentage is low, and it has very good antibacterial protection. PVDF has been blended with chitosan to improve the characteristics of the membrane. It is observed that the addition of silanized chitosan in the PVDF matrix enhances the water resistance of the membrane, showing the minimum value of the contact angle. Hence, this study has proved that the 2.0 g silane-chitosan/PVDF membrane is more applicable in the wastewater treatment industry than both pure PVDF and chitosan/PVDF membranes. This can be justified by the fact that the membrane has less tendency for wetting, higher tensile strength, and acts as an excellent barrier against bacterial contaminations.